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Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276) (MV612207)

Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276)
Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276)
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Overview
Catalog No.MV612207
Species reactivityHuman, Mouse, Rat
ApplicationsFCM
Host speciesRat
IsotypeIgG1, kappa
Clone IDm276
Clonality Monoclonal
Target CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q8VE98
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical).

Note For research use only.
Images
  • Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD276/B7-H3 Antibody (m276)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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