Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276) (MV612207)

Name: Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276)
Brand: abinScience
SKU: MV612207
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MV612207
Species reactivity	Human, Mouse, Rat
Applications	FCM
Host species	Rat
Clonality	Monoclonal
Isotype	IgG1, kappa
Clone ID	m276
Target	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8VE98
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical).
Note	For research use only.

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Overview