

| Número de catálogo | MV612137 |
|---|---|
| Reactividad de especies | Mouse |
| Aplicaciones | FCM |
| Especie huésped | Rat |
| Clonalidad | Monoclonal |
| Isotipo | IgG1 |
| ID de clon | MJ18 |
| Conjugación | APC |
| Objetivo | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Productos asociados | Rat IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Número de acceso | Q8VE98 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Fondo | CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical). |
| Nota | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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