Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384) (MT188107)

Name: Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384)
Brand: abinScience
SKU: MT188107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	MT188107
Reactividad de especies	Mouse
Aplicaciones	FCM, IF, IP, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	SAA1384
Objetivo	TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9QUN7
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. 1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042 2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091 3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456 5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037
Nota	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Mouse CD282/TLR2 Antibody (SAA1384)

Referencias

Datasheet

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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