Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE (MT188127)

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Catalog No.	MT188127
Description	Anti-Mouse CD282/TLR2 Antibody (SAA1384), PE [SAA1384] (MT188127) is a mouse monoclonal antibody detecting CD282 in FCM, IF, WB. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	FCM, IF, WB
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA1384
Conjugation	PE
Clonality	Monoclonal
Target	TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
Endotoxin level	Please contact with the lab for this information.
Accession	Q9QUN7
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. 1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042 2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091 3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456 5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE.pdf

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Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA1384), PE (MT188127)

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