Anti-Mouse ABCG2/CD338 Polyclonal Antibody (MV314014)

Name: Anti-Mouse ABCG2/CD338 Polyclonal Antibody
Brand: abinScience
SKU: MV314014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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Fiche technique
SDS

Aperçu

Numéro de catalogue

MV314014

Description

Anti-Mouse CD338/ABCG2 Polyclonal Antibody (MV314014) is a rabbit polyclonal antibody detecting Abcg2. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse CD338/ABCG2 (Asp35-Pro353).

Cible

ATP-binding cassette sub-family G member 2, Abcg2, Abcp, Bcrp1, Breast cancer resistance protein 1 homolog, Broad substrate specificity ATP-binding cassette transporter ABCG2, CD338, EC:7.6.2.2, Urate exporter

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q7TMS5

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Broad substrate specificity ATP-binding cassette transporter ABCG2 (CD338) is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate.

1. Allen, JD. et al. (1999) Cancer research 59, 4237-41. PMID: 10485464

2. Jonker, JW. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54. PMID: 12429862

3. Allen, JD. et al. (2002) Molecular cancer therapeutics 1, 417-25. PMID: 12477054

4. van Herwaarden, AE. et al. (2007) Molecular and cellular biology 27, 1247-53. PMID: 17145775

5. Takada, T. et al. (2018) Scientific reports 8, 11147. PMID: 30042379

6. Krishnamurthy, P. et al. (2004) The Journal of biological chemistry 279, 24218-25. PMID: 15044468

7. Millán-García, A. et al. (2024) International journal of molecular sciences 25. PMID: 39337371

Note

For research use only

Images

Reférences

Fiche technique

Anti-Mouse ABCG2/CD338 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Mouse ABCG2/CD338 Polyclonal Antibody (MV314014)

Aperçu

Images

Reférences

Fiche technique

SDS