Mouse CD338/ABCG2 Recombinant Protein (N-His) (MV314012)

Name: Mouse CD338/ABCG2 Recombinant Protein (N-His)
Brand: abinScience
SKU: MV314012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MV314012
Description	Recombinant Mouse CD338/ABCG2 Protein, N-His (MV314012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q7TMS5
Protein length	Asp35-Pro353
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ATP-binding cassette sub-family G member 2, Abcg2, Abcp, Bcrp1, Breast cancer resistance protein 1 homolog, Broad substrate specificity ATP-binding cassette transporter ABCG2, CD338, EC:7.6.2.2, Urate exporter
Background	Broad substrate specificity ATP-binding cassette transporter ABCG2 is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate. 1. Allen, JD. et al. (1999) Cancer research 59, 4237-41. PMID: 10485464 2. Jonker, JW. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54. PMID: 12429862 3. Allen, JD. et al. (2002) Molecular cancer therapeutics 1, 417-25. PMID: 12477054 4. van Herwaarden, AE. et al. (2007) Molecular and cellular biology 27, 1247-53. PMID: 17145775 5. Takada, T. et al. (2018) Scientific reports 8, 11147. PMID: 30042379 6. Krishnamurthy, P. et al. (2004) The Journal of biological chemistry 279, 24218-25. PMID: 15044468 7. Millán-García, A. et al. (2024) International journal of molecular sciences 25. PMID: 39337371
Note	For research use only

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Datasheet

Mouse CD338/ABCG2 Recombinant Protein (N-His).pdf

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Mouse CD338/ABCG2 Recombinant Protein (N-His) (MV314012)

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