

| Numéro de catalogue | MB625117 |
|---|---|
| Reactivité des espèces | Mouse |
| Applications | ELISA, FCM |
| Espèce hôte | Rat |
| Clonalité | Monoclonal |
| Isotype | IgG2b, kappa |
| ID de clone | 7G6 |
| Conjugaison | FITC |
| Cible | C3BR, Complement receptor type 1, CR1, CD35, C3b/C4b receptor |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Rat IgG2b, kappa Recombinant Isotype Control Antibody (ES26-5E12.4), FITC |
| Numéro d'accès | Q64735 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Complement component receptor 1-like protein (CD35/CR1) is a ~53 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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