Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (8C12) (MB625207)

Name: Anti-Mouse CD35/CR1/CD21b Recombinant Antibody (8C12)
Brand: abinScience
SKU: MB625207
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	MB625207
Species reactivity	Mouse
Applications	FCM
Host species	Rabbit
Isotype	IgG
Clone ID	8C12
Clonality	Monoclonal
Target	C3BR, Complement receptor type 1, CR1, CD35, C3b/C4b receptor
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q64735
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Complement component receptor 1-like protein (CD35/CR1) is a ~53 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Note	For research use only.

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Formula

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Overview