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Anti-Mouse CD35 Recombinant Antibody (8C12), FITC (MB625217)

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Aperçu
Numéro de catalogueMB625217
Reactivité des espècesMouse
ApplicationsFCM
Espèce hôteRabbit
ClonalitéMonoclonal
IsotypeIgG
ID de clone8C12
ConjugaisonFITC
Cible C3BR, Complement receptor type 1, CR1, CD35, C3b/C4b receptor
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Rabbit IgG Recombinant Isotype Control Antibody (HyHEL-10), FITC
Numéro d'accès Q64735
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Complement component receptor 1-like protein (CD35/CR1) is a ~53 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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