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| カタログ番号 | MB625217 |
|---|---|
| 種反応性 | Mouse |
| アプリケーション | FCM |
| 宿主種 | Rabbit |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 8C12 |
| 抱合 | FITC |
| ターゲット | C3BR, Complement receptor type 1, CR1, CD35, C3b/C4b receptor |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Rabbit IgG Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| アクセッション番号 | Q64735 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Complement component receptor 1-like protein (CD35/CR1) is a ~53 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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