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Anti-Mouse CD37 Recombinant Antibody (252-3#) (MY564107)

Anti-Mouse CD37 Recombinant Antibody (252-3#)
Anti-Mouse CD37 Recombinant Antibody (252-3#)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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Vista general
Número de catálogoMY564107
Reactividad de especiesMouse
AplicacionesELISA, FCM, Neutralization
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clon252-3#
Objetivo Leukocyte antigen CD37, CD37
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q61470
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Knobeloch, KP. et al. (2000) Molecular and cellular biology 20, 5363-9. PMID: 10891477
2. van Spriel, AB. et al. (2012) Science signaling 5, ra82. PMID: 23150881
3. Gartlan, KH. et al. (2013) European journal of immunology 43, 1208-19. PMID: 23420539
4. Wee, JL. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 195, 5770-9. PMID: 26566675
Nota For research use only.
Imágenes
  • Anti-Mouse CD37 Recombinant Antibody (252-3#)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD37 Antibody (252-3#)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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