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Anti-Mouse CD37 Recombinant Antibody (252-3#) (MY564107)

Anti-Mouse CD37 Recombinant Antibody (252-3#)
Anti-Mouse CD37 Recombinant Antibody (252-3#)
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  • 100ug
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Aperçu
Numéro de catalogueMY564107
Reactivité des espècesMouse
ApplicationsELISA, FCM, Neutralization
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de clone252-3#
Cible Leukocyte antigen CD37, CD37
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q61470
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Knobeloch, KP. et al. (2000) Molecular and cellular biology 20, 5363-9. PMID: 10891477
2. van Spriel, AB. et al. (2012) Science signaling 5, ra82. PMID: 23150881
3. Gartlan, KH. et al. (2013) European journal of immunology 43, 1208-19. PMID: 23420539
4. Wee, JL. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 195, 5770-9. PMID: 26566675
Note For research use only.
Images
  • Anti-Mouse CD37 Recombinant Antibody (252-3#)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD37 Antibody (252-3#)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
Recommandation

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