Anti-Mouse CD37 Recombinant Antibody (252-3#) (MY564107)

Name: Anti-Mouse CD37 Recombinant Antibody (252-3#)
Brand: abinScience
SKU: MY564107
Price: 196 USD
Availability: InStock

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Обзор

Каталожный номер	MY564107
Реактивность видов	Mouse
Применения	ELISA, FCM, Neutralization
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	252-3#
Цель	Leukocyte antigen CD37, CD37
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q61470
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT. 1. Knobeloch, KP. et al. (2000) Molecular and cellular biology 20, 5363-9. PMID: 10891477 2. van Spriel, AB. et al. (2012) Science signaling 5, ra82. PMID: 23150881 3. Gartlan, KH. et al. (2013) European journal of immunology 43, 1208-19. PMID: 23420539 4. Wee, JL. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 195, 5770-9. PMID: 26566675
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Mouse CD37 Antibody (252-3#)

Ссылки

Даташит

Anti-Mouse CD37 Recombinant Antibody (252-3#).pdf

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Formula

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