





| Numéro de catalogue | MF998107 |
|---|---|
| Reactivité des espèces | Mouse |
| Applications | in vivo CD4+ T cell depletion, FCM, WB |
| Espèce hôte | Rat |
| Clonalité | Monoclonal |
| Isotype | IgG2b |
| ID de clone | GK1.5 |
| Applications testées | WB |
| Cible | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P06332 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. |

Detects CD4 in indirect ELISAs.

Detects recombinant mouse CD4 (Catalog No: MF998011) in indirect ELISA

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant mouse CD4 (Catalog No: MF998012)
Lane 2: negative control




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