

| Catalog No. | MF998117 |
|---|---|
| Description |
Anti-Mouse CD4 Antibody (GK1.5), FITC [GK1.5] (MF998117) is a rat monoclonal antibody detecting CD4 in FCM. Suitable for Mouse.
Highlights
|
| Species reactivity | Mouse |
| Applications | FCM |
| Host species | Rat |
| Isotype | IgG2b |
| Clone ID | GK1.5 |
| Conjugation | FITC |
| Clonality | Monoclonal |
| Target | T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P06332 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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