Anti-Mouse CD83 Recombinant Antibody (SAA2066), PE (MX237127)

Name: Anti-Mouse CD83 Recombinant Antibody (SAA2066), PE
Brand: abinScience
SKU: MX237127
Price: 256 USD
Availability: InStock

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Каталожный номер	MX237127
Реактивность видов	Human, Mouse
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	SAA2066
Конъюгация	PE
Цель	CD83, hCD83, CD83 antigen, B-cell activation protein, Cell surface protein HB15
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE
Номер доступа	O88324
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	CD83 antigen is a ~21 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections. 1. von Rohrscheidt, J. et al. (2016) The Journal of experimental medicine 213, 1685-94. PMID: 27503071 2. Liu, H. et al. (2016) The Journal of experimental medicine 213, 1695-703. PMID: 27503069 3. Wild, AB. et al. (2019) JCI insight 4. PMID: 31527313
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD83 Recombinant Antibody (SAA2066), PE.pdf

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