Anti-Mouse CD83 Recombinant Antibody (SAA2066) (MX237107)

Name: Anti-Mouse CD83 Recombinant Antibody (SAA2066)
Brand: abinScience
SKU: MX237107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	MX237107
Species reactivity	Human, Mouse
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA2066
Clonality	Monoclonal
Target	CD83, hCD83, CD83 antigen, B-cell activation protein, Cell surface protein HB15
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O88324
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	CD83 antigen is a ~21 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections. 1. von Rohrscheidt, J. et al. (2016) The Journal of experimental medicine 213, 1685-94. PMID: 27503071 2. Liu, H. et al. (2016) The Journal of experimental medicine 213, 1695-703. PMID: 27503069 3. Wild, AB. et al. (2019) JCI insight 4. PMID: 31527313
Note	For research use only.

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Datasheet

Anti-Mouse CD83 Recombinant Antibody (SAA2066).pdf

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Anti-Mouse CD83 Recombinant Antibody (SAA2066) (MX237107)

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