Anti-Mouse B7-2/CD86 Recombinant Antibody (GL1) (MW776107)

Name: Anti-Mouse B7-2/CD86 Recombinant Antibody (GL1)
Brand: abinScience
SKU: MW776107
Price: 163 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MW776107
Reactivité des espèces	Mouse
Applications	FCM
Espèce hôte	Rat
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	GL1
Cible	BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P42082
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	T-lymphocyte activation antigen CD86 (B7-2) is a ~34 kDa protein. Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells by acting as a ligand for the CD28 receptor which is constitutively expressed on the cell surface of T-cells. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. 1. Lucas, CR. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 723-36. PMID: 23241883 2. Freeman, GJ. et al. (1993) The Journal of experimental medicine 178, 2185-92. PMID: 7504059 3. Chen, C. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 4929-36. PMID: 7513726
Note	For research use only.

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SDS-PAGE for Anti-Mouse CD86/B7-2 Antibody (GL1)

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Anti-Mouse B7-2/CD86 Recombinant Antibody (GL1).pdf

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