中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | MW776107 |
|---|---|
| 種反応性 | Mouse |
| アプリケーション | FCM |
| 宿主種 | Rat |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a, kappa |
| クローンID | GL1 |
| ターゲット | BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P42082 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | T-lymphocyte activation antigen CD86 (B7-2) is a ~34 kDa protein. Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells by acting as a ligand for the CD28 receptor which is constitutively expressed on the cell surface of T-cells. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. 1. Lucas, CR. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 723-36. PMID: 23241883 2. Freeman, GJ. et al. (1993) The Journal of experimental medicine 178, 2185-92. PMID: 7504059 3. Chen, C. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 4929-36. PMID: 7513726 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Mouse CD86/B7-2 Antibody (GL1)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
