

| Número de catálogo | MF844014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse DGAT1 Polyclonal Antibody (MF844014) is a rabbit polyclonal antibody detecting DGAT1. Suitable for Mouse and Rat.
Highlights
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| Reactividad de especies | Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse DGAT1 (Gly2-Ser92). | ||||||||
| Objetivo | ACAT-related gene product 1, AGRP1, ARAT, Acyl-CoA retinol O-fatty-acyltransferase, DGAT, DGAT1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase, EC:2.3.1.20, EC:2.3.1.76, Retinol O-fatty-acyltransferase | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Z2A7 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Diacylglycerol O-acyltransferase 1 (DGAT1) is a ~56 kDa protein. Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. 1. Yen, CL. et al. (2005) Journal of lipid research 46, 1502-11. PMID: 15834126 2. Shih, MY. et al. (2009) The Journal of biological chemistry 284, 4292-9. PMID: 19028692 3. McFie, PJ. et al. (2010) The Journal of biological chemistry 285, 37377-87. PMID: 20876538 4. Qi, J. et al. (2012) Journal of lipid research 53, 1106-16. PMID: 22493088 5. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 6. Buhman, KK. et al. (2002) The Journal of biological chemistry 277, 25474-9. PMID: 11959864 | ||||||||
| Nota | For research use only |
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