

| Numéro de catalogue | MF844014 | ||||||||
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| Description |
Anti-Mouse DGAT1 Polyclonal Antibody (MF844014) is a rabbit polyclonal antibody detecting DGAT1. Suitable for Mouse and Rat.
Highlights
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| Reactivité des espèces | Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse DGAT1 (Gly2-Ser92). | ||||||||
| Cible | ACAT-related gene product 1, AGRP1, ARAT, Acyl-CoA retinol O-fatty-acyltransferase, DGAT, DGAT1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase, EC:2.3.1.20, EC:2.3.1.76, Retinol O-fatty-acyltransferase | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Z2A7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Diacylglycerol O-acyltransferase 1 (DGAT1) is a ~56 kDa protein. Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. 1. Yen, CL. et al. (2005) Journal of lipid research 46, 1502-11. PMID: 15834126 2. Shih, MY. et al. (2009) The Journal of biological chemistry 284, 4292-9. PMID: 19028692 3. McFie, PJ. et al. (2010) The Journal of biological chemistry 285, 37377-87. PMID: 20876538 4. Qi, J. et al. (2012) Journal of lipid research 53, 1106-16. PMID: 22493088 5. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 6. Buhman, KK. et al. (2002) The Journal of biological chemistry 277, 25474-9. PMID: 11959864 | ||||||||
| Note | For research use only |
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