

| Каталожный номер | MB164014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Mouse EFNA1 Polyclonal Antibody (MB164014) is a rabbit polyclonal antibody detecting EFNA1 in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| Реактивность видов | Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Mouse EFNA1 (Met1-Ser182). | ||||||||
| Цель | Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) [Cleaved into: Ephrin-A1, secreted form] | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P52793 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ephrin-A1 (EFNA1) is a ~23 kDa protein. Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis. 1. Hunter, SG. et al. (2006) Molecular and cellular biology 26, 4830-42. PMID: 16782872 2. Fang, WB. et al. (2008) The Journal of biological chemistry 283, 16017-26. PMID: 18387945 3. Frieden, LA. et al. (2010) Developmental dynamics : an official publication of the American Association of Anatomists 239, 3226-34. PMID: 20960543 4. Fu, WY. et al. (2007) Nature neuroscience 10, 67-76. PMID: 17143272 | ||||||||
| Примечание | For research use only. |



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