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Anti-Mouse IGF-I/IGF-1 Polyclonal Antibody (MY095014)

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概要
カタログ番号MY095014
説明
Anti-Mouse IGF1 Polyclonal Antibody (MY095014) is a rabbit polyclonal antibody detecting IGF1. Suitable for Rat, Human, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Mouse IGF1 (Val65-Lys134).
ターゲット IBP1, IGF-1, IGF-I, IGF1, Insulin-like growth factor 1, Insulin-like growth factor I, MGF, Mechano growth factor, Somatomedin-C
エンドトキシンレベル Please contact with the lab for this information.
精製 Purified by antigen affinity column.
アクセッション番号 P05017
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Insulin-like growth factor 1 (IGF1) is a ~17 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.

1. Cao, P. et al. (2011) Cell 145, 300-11. PMID: 21496647
注意事項 For research use only
イメージ
参考文献
Formula
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Formula
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