InVivoMAb Anti-Mouse IGF-I/IGF-1 Antibody (Iv0223) (MY095010)

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Overview

Catalog No.	MY095010
Description	InVivoMAb Anti-Mouse IGF1 Antibody (Iv0223) [Iv0223] (MY095010) is a human monoclonal antibody detecting Insulin-like growth factor I in Blocking, ELISA. Suitable for Mouse.
Species reactivity	Mouse
Applications	Blocking, ELISA
Host species	Human
Isotype	IgG1
Clone ID	Iv0223
Clonality	Monoclonal
Target	Insulin-like growth factor I, IGF-I, Somatomedin, Igf1, Igf-1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05017
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Insulin-like growth factor 1 (IGF1) is a ~17 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. 1. Cao, P. et al. (2011) Cell 145, 300-11. PMID: 21496647
Note	For research use only. Not suitable for clinical or therapeutic use.

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InVivoMAb Anti-Mouse IGF-I/IGF-1 Antibody (Iv0223).pdf

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InVivoMAb Anti-Mouse IGF-I/IGF-1 Antibody (Iv0223) (MY095010)

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