

| Catalog No. | MY095014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse IGF1 Polyclonal Antibody (MY095014) is a rabbit polyclonal antibody detecting IGF1. Suitable for Rat, Human, and Mouse.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse IGF1 (Val65-Lys134). | ||||||||
| Target | IBP1, IGF-1, IGF-I, IGF1, Insulin-like growth factor 1, Insulin-like growth factor I, MGF, Mechano growth factor, Somatomedin-C | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P05017 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Insulin-like growth factor 1 (IGF1) is a ~17 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. 1. Cao, P. et al. (2011) Cell 145, 300-11. PMID: 21496647 | ||||||||
| Note | For research use only |




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