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Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987) (MV121013)

Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987)
Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987)
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概要
カタログ番号MV121013
種反応性Mouse
アプリケーションELISA, in vivo research
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2a, kappa
クローンIDSAA1987
ターゲット Interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Il31ra, Glmr
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q8K5B1
RRID

Anti-Mouse IL-31RA/NR10 Antibody (SAA1987) (abinScience Cat# MV121013, RRID:AB_3727752)
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形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:2000-1:20000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Interleukin-31 receptor subunit alpha (IL31RA) is a ~80 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
2. Cevikbas, F. et al. (2014) The Journal of allergy and clinical immunology 133, 448-60. PMID: 24373353
3. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091
注意事項 For research use only.
イメージ
  • Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse IL-31RA/NR10 Antibody (SAA1987)

参考文献
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