Anti-Mouse IL-31RA Polyclonal Antibody (MV121014)

Name: Anti-Mouse IL-31RA Polyclonal Antibody
Brand: abinScience
SKU: MV121014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

MV121014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL31RA (Val19-Glu210).

Target

Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (GLM-R) (mGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (Novel cytokine receptor 10) (NR10) (ZcytoR17)

Purification

Purified by antigen affinity column.

Accession

Q8K5B1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-31 receptor subunit alpha (IL31RA) is a ~80 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896

2. Cevikbas, F. et al. (2014) The Journal of allergy and clinical immunology 133, 448-60. PMID: 24373353

3. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091

Note

For research use only.

Images

References

Datasheet

Anti-Mouse IL-31RA Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Mouse IL-31RA Polyclonal Antibody (MV121014)

Overview

Images

References

Datasheet

SDS

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