Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987) (MV121013)

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50ug
100ug
1mg

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Overview

Catalog No.

MV121013

Description

Anti-Mouse IL-31RA/NR10 Antibody (SAA1987) [SAA1987] (MV121013) is a mouse monoclonal antibody detecting IL-31RA in ELISA. Suitable for Mouse.

Species reactivity

Mouse

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1987

Clonality

Monoclonal

Target

Interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Il31ra, Glmr

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8K5B1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Interleukin-31 receptor subunit alpha (IL31RA) is a ~80 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896

2. Cevikbas, F. et al. (2014) The Journal of allergy and clinical immunology 133, 448-60. PMID: 24373353

3. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse IL-31RA/NR10 Antibody (SAA1987)

References

Datasheet

Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL-31RA/NR10 Recombinant Antibody (SAA1987) (MV121013)

Overview

Images

References

Datasheet

SDS

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