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| カタログ番号 | MW632013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Mouse | ||||
| アプリケーション | ELISA, FCM | ||||
| 宿主種 | mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | BAK209B11 | ||||
| ターゲット | IL-13, IL13, Interleukin-13, NC30 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P20109 | ||||
| RRID | Anti-Mouse IL13 Antibody (BAK209B11) (abinScience Cat# MW632013, RRID:AB_3725661) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Interleukin-13 (IL13) is a ~14 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Finkelman, FD. et al. (2004) Immunological reviews 201, 139-55. PMID: 15361238 2. Zhang, M. et al. (2021) Journal of immunology (Baltimore, Md. : 1950) 207, 3070-3080. PMID: 34789557 3. Mayer, JU. et al. (2021) Nature immunology 22, 1538-1550. PMID: 34795444 4. Takeda, K. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 3220-2. PMID: 8871614 5. Duffen, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1347-1359. PMID: 29305434 | ||||
| 注意事項 | For research use only. |
Detects Mouse IL13 in indirect ELISAs.
SDS-PAGE for Anti-Mouse IL13 Antibody (BAK209B11).
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