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Anti-Mouse IL-22 Recombinant Antibody (368D04) (MV999013)

Anti-Mouse IL-22 Recombinant Antibody (368D04)
Anti-Mouse IL-22 Recombinant Antibody (368D04)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoMV999013
Reactividad de especiesHuman, Mouse
AplicacionesELISA, FCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clon368D04
Objetivo Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9JJY9
RRID Anti-Mouse IL22 Antibody (368D04) (abinScience Cat# MV999013, RRID:AB_3725662)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Interleukin-22 (IL22) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3.

1. Saxton, RA. et al. (2021) Immunity 54, 660-672.e9. PMID: 33852830
2. Ulu, A. et al. (2022) Toxicology and applied pharmacology 446, 116044. PMID: 35525330
3. Delbue, D. et al. (2021) Frontiers in medicine 8, 656047. PMID: 33912578
4. Weathington, NM. et al. (2014) The Journal of biological chemistry 289, 17610-9. PMID: 24742671
Nota For research use only.
Imágenes
  • Anti-Mouse IL-22 Recombinant Antibody (368D04)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse IL22 Antibody (368D04)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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