Anti-Mouse IL-22 Recombinant Antibody (368D04) (MV999013)

Name: Anti-Mouse IL-22 Recombinant Antibody (368D04)
Brand: abinScience
SKU: MV999013
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MV999013

Reactivité des espèces

Human, Mouse

Applications

ELISA, FCM

Espèce hôte

Rat

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

368D04

Cible

Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9JJY9

RRID

Anti-Mouse IL22 Antibody (368D04) (abinScience Cat# MV999013, RRID:AB_3725662)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Interleukin-22 (IL22) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3.

1. Saxton, RA. et al. (2021) Immunity 54, 660-672.e9. PMID: 33852830

2. Ulu, A. et al. (2022) Toxicology and applied pharmacology 446, 116044. PMID: 35525330

3. Delbue, D. et al. (2021) Frontiers in medicine 8, 656047. PMID: 33912578

4. Weathington, NM. et al. (2014) The Journal of biological chemistry 289, 17610-9. PMID: 24742671

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse IL22 Antibody (368D04)

Reférences

Fiche technique

Anti-Mouse IL-22 Recombinant Antibody (368D04).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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