Anti-Mouse IL24 Recombinant Antibody (SAA2595) (MC472023)

Name: Anti-Mouse IL24 Recombinant Antibody (SAA2595)
Brand: abinScience
SKU: MC472023
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MC472023
Reactivité des espèces	Mouse
Applications	ELISA, FCM, Neutralization
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	SAA2595
Cible	IL-24, IL-4-induced secreted protein, Il24, Interleukin-24, MDA-7, Mda7, Melanoma differentiation-associated gene 7 protein, Th2-specific cytokine FISP
Niveau d'endotoxines	<10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q925S4
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Interleukin-24 (IL24) is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. 1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348 2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201
Note	For research use only

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Anti-Mouse IL24 Recombinant Antibody (SAA2595).pdf

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