

| Каталожный номер | MA497014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Mouse MAG/Myelin-associated glycoprotein Polyclonal Antibody (MA497014) is a rabbit polyclonal antibody detecting MAG/Myelin-associated glycoprotein in ELISA, IHC, WB. Suitable for Rattus norvegicus, Human, and Mus musculus.
Highlights
|
||||||||
| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Mouse MAG/Myelin-associated glycoprotein (Asp235-Glu410). | ||||||||
| Цель | MAG/Myelin-associated glycoprotein | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P20917 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||||
| Информация об использовании продукта |
| ||||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Альтернативные названия | Myelin-associated glycoprotein, Siglec-4a, Mag | ||||||||
| Фон | Myelin-associated glycoprotein (MAG) is a ~69 kDa protein. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane. Negative regulator of neurite outgrowth that inhibits axon longitudinal growth. 1. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 2. Pronker, MF. et al. (2016) Nature communications 7, 13584. PMID: 27922006 3. Kelm, S. et al. (1994) Current biology : CB 4, 965-72. PMID: 7533044 4. Schachner, M. et al. (2000) Glia 29, 154-65. PMID: 10625334 5. Li, C. et al. (1994) Nature 369, 747-50. PMID: 7516497 6. Bartsch, S. et al. (1997) Brain research 762, 231-4. PMID: 9262180 7. Li, C. et al. (1998) Journal of neuroscience research 51, 210-7. PMID: 9469574 8. Yin, X. et al. (1998) The Journal of neuroscience : the official journal of the Society for Neuroscience 18, 1953-62. PMID: 9482781 9. Fujita, N. et al. (1998) The Journal of neuroscience : the official journal of the Society for Neuroscience 18, 1970-8. PMID: 9482783 10. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717 | ||||||||
| Примечание | For research use only. |



Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
Быстрый доступ
Свяжитесь с нами
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский