

| Número de catálogo | MB123207 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Mouse | ||||
| Aplicaciones | Blocking, ELISA, FCM | ||||
| Especie huésped | Rat | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1, kappa | ||||
| ID de clon | CX5 | ||||
| Objetivo | NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d | ||||
| Nivel de endotoxinas | <1 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Productos asociados | pH 7.4 Dilution Buffer | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | O54709 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||
| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF. | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Mouse NKG2D Antibody (CX5)




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