Anti-Mouse NKG2D Recombinant Antibody (MI-6), FITC (MB123117)

Name: Anti-Mouse NKG2D Recombinant Antibody (MI-6), FITC
Brand: abinScience
SKU: MB123117
Price: 223 USD
Availability: InStock

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Overview

Catalog No.	MB123117
Species reactivity	Mouse
Applications	ELISA, FCM
Host species	Rat
Isotype	IgG2a, lambda
Clone ID	MI-6
Conjugation	FITC
Clonality	Monoclonal
Target	NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
Endotoxin level	Please contact with the lab for this information.
Associated products	Rat IgG2a Recombinant Isotype Control Antibody (SPE-7), FITC
Accession	O54709
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse NKG2D Recombinant Antibody (MI-6), FITC.pdf

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Anti-Mouse NKG2D Recombinant Antibody (MI-6), FITC (MB123117)

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