Anti-Mouse NKG2D Recombinant Antibody (CX5) (MB123207)

Name: Anti-Mouse NKG2D Recombinant Antibody (CX5)
Brand: abinScience
SKU: MB123207
Price: 191 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MB123207

Species reactivity

Mouse

Applications

Blocking, ELISA, FCM

Host species

Rat

Isotype

IgG1, kappa

Clone ID

CX5

Clonality

Monoclonal

Target

NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d

Endotoxin level

<1 EU/mg

Purity

>95% as determined by SDS-PAGE.

Associated products

pH 7.4 Dilution Buffer

Purification

Protein A/G purified from cell culture supernatant.

Accession

O54709

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse NKG2D Antibody (CX5)

References

Datasheet

Anti-Mouse NKG2D Recombinant Antibody (CX5).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse NKG2D Recombinant Antibody (CX5) (MB123207)

Overview

Images

References

Datasheet

SDS

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