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Anti-Mouse OSTN Polyclonal Antibody (MX160014)

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Vista general
Número de catálogoMX160014
Descripción
Anti-Mouse OSTN Polyclonal Antibody (MX160014) is a rabbit polyclonal antibody detecting OSTN in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesMouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse OSTN (Phe26-Gly130).
Objetivo OSTN, Osteocrin, Musclin
Purificación Purified by antigen affinity column.
Número de acceso P61364
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Osteocrin (OSTN) is a ~14 kDa protein. Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle.

1. Thomas, G. et al. (2003) The Journal of biological chemistry 278, 50563-71. PMID: 14523025
2. Moffatt, P. et al. (2007) The Journal of biological chemistry 282, 36454-62. PMID: 17951249
3. Subbotina, E. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 16042-7. PMID: 26668395
4. Nishizawa, H. et al. (2004) The Journal of biological chemistry 279, 19391-5. PMID: 15044443
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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