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Anti-Mouse PTHLH Polyclonal Antibody (MY340014)

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Vista general
Número de catálogoMY340014
Descripción
Anti-Mouse PTHLH Polyclonal Antibody (MY340014) is a rabbit polyclonal antibody detecting PTHLH. Suitable for Mouse and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesMouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse PTHLH (Lys35-His175).
Objetivo Osteostatin, PLP, PTH-rP, PTHLH, PTHRP, PTHrP, PTHrP[1-36], PTHrP[107-139], PTHrP[38-94], Parathyroid hormone-like protein, Parathyroid hormone-related protein
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P22858
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Parathyroid hormone-related protein (PTHLH) is a ~20 kDa protein. Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs.

1. Karaplis, AC. et al. (1994) Genes & development 8, 277-89. PMID: 8314082
2. Lee, K. et al. (1996) Endocrinology 137, 5109-18. PMID: 8895385
3. Guo, J. et al. (2010) Endocrinology 151, 3502-13. PMID: 20501677
4. Hens, JR. et al. (2007) Development (Cambridge, England) 134, 1221-30. PMID: 17301089
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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