Mouse PTHLH Recombinant Protein (N-His-KSI) (MY340012)

Name: Mouse PTHLH Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: MY340012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MY340012
Description	Recombinant Mouse PTHLH Protein, N-His-KSI (MY340012) expressed in E. coli, spanning Lys35-His175. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P22858
Protein length	Lys35-His175
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	31.92 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Osteostatin, PLP, PTH-rP, PTHLH, PTHRP, PTHrP, PTHrP[1-36], PTHrP[107-139], PTHrP[38-94], Parathyroid hormone-like protein, Parathyroid hormone-related protein
Background	Parathyroid hormone-related protein is a ~20 kDa protein. Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. 1. Karaplis, AC. et al. (1994) Genes & development 8, 277-89. PMID: 8314082 2. Lee, K. et al. (1996) Endocrinology 137, 5109-18. PMID: 8895385 3. Guo, J. et al. (2010) Endocrinology 151, 3502-13. PMID: 20501677 4. Hens, JR. et al. (2007) Development (Cambridge, England) 134, 1221-30. PMID: 17301089
Note	For research use only

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Datasheet

Mouse PTHLH Recombinant Protein (N-His-KSI).pdf

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Mouse PTHLH Recombinant Protein (N-His-KSI) (MY340012)

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