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Anti-Mouse PTHLH Polyclonal Antibody (MY340014)

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Overview
Catalog No.MY340014
Description
Anti-Mouse PTHLH Polyclonal Antibody (MY340014) is a rabbit polyclonal antibody detecting PTHLH. Suitable for Mouse and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse PTHLH (Lys35-His175).
Target Osteostatin, PLP, PTH-rP, PTHLH, PTHRP, PTHrP, PTHrP[1-36], PTHrP[107-139], PTHrP[38-94], Parathyroid hormone-like protein, Parathyroid hormone-related protein
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P22858
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Parathyroid hormone-related protein (PTHLH) is a ~20 kDa protein. Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs.

1. Karaplis, AC. et al. (1994) Genes & development 8, 277-89. PMID: 8314082
2. Lee, K. et al. (1996) Endocrinology 137, 5109-18. PMID: 8895385
3. Guo, J. et al. (2010) Endocrinology 151, 3502-13. PMID: 20501677
4. Hens, JR. et al. (2007) Development (Cambridge, England) 134, 1221-30. PMID: 17301089
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Mouse PTHLH Polyclonal Antibody

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