Anti-Mouse PTHLH Polyclonal Antibody (MY340014)

Name: Anti-Mouse PTHLH Polyclonal Antibody
Brand: abinScience
SKU: MY340014
Price: 168 USD
Availability: InStock

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Fiche technique
SDS

Aperçu

Numéro de catalogue

MY340014

Description

Anti-Mouse PTHLH Polyclonal Antibody (MY340014) is a rabbit polyclonal antibody detecting PTHLH. Suitable for Mouse and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse PTHLH (Lys35-His175).

Cible

Osteostatin, PLP, PTH-rP, PTHLH, PTHRP, PTHrP, PTHrP[1-36], PTHrP[107-139], PTHrP[38-94], Parathyroid hormone-like protein, Parathyroid hormone-related protein

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P22858

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Parathyroid hormone-related protein (PTHLH) is a ~20 kDa protein. Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs.

1. Karaplis, AC. et al. (1994) Genes & development 8, 277-89. PMID: 8314082

2. Lee, K. et al. (1996) Endocrinology 137, 5109-18. PMID: 8895385

3. Guo, J. et al. (2010) Endocrinology 151, 3502-13. PMID: 20501677

4. Hens, JR. et al. (2007) Development (Cambridge, England) 134, 1221-30. PMID: 17301089

Note

For research use only

Images

Reférences

Fiche technique

Anti-Mouse PTHLH Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai