

| Каталожный номер | MY039013 | ||||||
|---|---|---|---|---|---|---|---|
| Реактивность видов | Mouse | ||||||
| Применения | ELISA, IF, IHC, IP, RIA, WB | ||||||
| Хозяинский вид | Rat | ||||||
| Клоональность | Monoclonal | ||||||
| Изотип | IgG2a, kappa | ||||||
| ID клона | PAb242 | ||||||
| Цель | Antigen NY-CO-13, Cellular tumor antigen p53, P53, Tumor suppressor p53, TP53, Phosphoprotein p53 | ||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||||
| Номер доступа | P02340 | ||||||
| RRID | Anti-Mouse TP53/p53 Antibody (PAb242) (abinScience Cat# MY039013, RRID:AB_3725644) |
||||||
| Форма | Liquid | ||||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||
| Информация об использовании продукта |
| ||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Фон | Cellular tumor antigen p53 (TP53) is a ~43 kDa protein. Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. 1. Allton, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 11612-6. PMID: 19556538 2. Huarte, M. et al. (2010) Cell 142, 409-19. PMID: 20673990 3. Vaseva, AV. et al. (2012) Cell 149, 1536-48. PMID: 22726440 4. Miki, T. et al. (2013) Nature communications 4, 2444. PMID: 24051492 | ||||||
| Примечание | For research use only. |

Detects Recombinant Mouse TP53/p53 Protein, N-His (Cat No.: MY039012) in indirect ELISA.
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]


+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский