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Каталожный номерMP967014
Описание
Anti-Mouse TREML4 Polyclonal Antibody (MP967014) is a rabbit polyclonal antibody detecting TREML4 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовMouse
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Mouse TREML4 (Val31-Pro138).
Цель Trem-like transcript 4 protein (TLT-4) (Triggering receptor expressed on myeloid cells-like protein 3) (Triggering receptor expressed on myeloid cells-like protein 4)
Очистка Purified by antigen affinity column.
Номер доступа Q3LRV9
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Trem-like transcript 4 protein (TREML4) is a ~29 kDa protein. Positively regulates Toll-like receptor signaling via TLR7, TLR9 and TLR13 in neutrophils and splenic macrophages. Regulates TLR7 signaling by controlling ligand-induced recruitment of TLR7 from the endoplasmic reticulum to endosomes and lysosomes. Positively regulates Toll-like receptor TLR9-induced production of inflammatory cytokines but is dispensable for IFNB1 production. Involved in the anti-viral response to several viruses including influenza virus, vesicular stomatitis virus and cytomegalovirus. Binds to late apoptotic, and necrotic cells, but not living or early apoptotic cells, but is not essential for uptake of dying cells by dendritic cells (DCs).

1. Ramirez-Ortiz, ZG. et al. (2015) Nature immunology 16, 495-504. PMID: 25848864
2. Hemmi, H. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 1278-86. PMID: 19155473
3. Hemmi, H. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1147-55. PMID: 22210914
Примечание For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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