Mouse TREML4 Recombinant Protein (N-His) (MP967022)

Name: Mouse TREML4 Recombinant Protein (N-His)
Brand: abinScience
SKU: MP967022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MP967022
Description	Recombinant Mouse TREML4 Protein, N-His (MP967022) expressed in E. coli, spanning Ser29-Pro138. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q3LRV9
Protein length	Ser29-Pro138
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	14.94 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	TLT-4, TLT4, TREML4, Trem-like transcript 4 protein, Triggering receptor expressed on myeloid cells-like protein 4
Background	Trem-like transcript 4 protein is a ~29 kDa protein. Positively regulates Toll-like receptor signaling via TLR7, TLR9 and TLR13 in neutrophils and splenic macrophages. Regulates TLR7 signaling by controlling ligand-induced recruitment of TLR7 from the endoplasmic reticulum to endosomes and lysosomes. Positively regulates Toll-like receptor TLR9-induced production of inflammatory cytokines but is dispensable for IFNB1 production. Involved in the anti-viral response to several viruses including influenza virus, vesicular stomatitis virus and cytomegalovirus. Binds to late apoptotic, and necrotic cells, but not living or early apoptotic cells, but is not essential for uptake of dying cells by dendritic cells (DCs). 1. Ramirez-Ortiz, ZG. et al. (2015) Nature immunology 16, 495-504. PMID: 25848864 2. Hemmi, H. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 1278-86. PMID: 19155473 3. Hemmi, H. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1147-55. PMID: 22210914
Note	For research use only

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Datasheet

Mouse TREML4 Recombinant Protein (N-His).pdf

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Mouse TREML4 Recombinant Protein (N-His) (MP967022)

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