Anti-Mouse WDR45 Monoclonal Antibody (1A445) (MP297015)

Name: Anti-Mouse WDR45 Monoclonal Antibody (1A445)
Brand: abinScience
SKU: MP297015
Price: 194 USD
Availability: InStock

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Numéro de catalogue	MP297015
Description	Anti-Mouse WDR45 Monoclonal Antibody (1A445) [1A445] (MP297015) is a mouse monoclonal antibody detecting Wdr45 in ELISA, WB. Suitable for Mouse. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Reactivité des espèces	Mouse
Applications	ELISA, WB
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2b
ID de clone	1A445
Immunogène	Recombinant Mouse WDR45 protein.
Cible	WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat domain X-linked 1, WD repeat-containing protein 45, Wdr45, DXImx38e, Wdrx1, Wipi4
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q91VM3
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	WD repeat domain phosphoinositide-interacting protein 4 (WDR45) is a ~39 kDa protein. Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Binds phosphatidylinositol 3-phosphate (PtdIns3P). Activated by the STK11/AMPK signaling pathway upon starvation, WDR45 is involved in autophagosome assembly downstream of WIPI2, regulating the size of forming autophagosomes. Together with WIPI1, promotes ATG2 (ATG2A or ATG2B)-mediated lipid transfer by enhancing ATG2-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes. Probably recruited to membranes through its PtdIns3P activity. 1. Saitsu, H. et al. (2013) Nature genetics 45, 445-9, 449e1. PMID: 23435086 2. Bakula, D. et al. (2017) Nature communications 8, 15637. PMID: 28561066 3. Maeda, S. et al. (2019) eLife 8. PMID: 31271352
Note	For research use only.

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Anti-Mouse WDR45 Monoclonal Antibody (1A445).pdf

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Anti-Mouse WDR45 Monoclonal Antibody (1A445) (MP297015)

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