Anti-MPO Polyclonal Antibody (HY413014)

Name: Anti-MPO Polyclonal Antibody
Brand: abinScience
SKU: HY413014
Price: 96 USD
Availability: InStock

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Vista general

Número de catálogo

HY413014

Descripción

Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human MPO (Val165-Gly278).

Objetivo

Myeloperoxidase, MPO

Purificación

Purified by antigen affinity column.

Número de acceso

P05164

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.

1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160

2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971

Nota

For research use only.

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