Anti-Human MPO Monoclonal Antibody (1A524) (HY413035)

Name: Anti-Human MPO Monoclonal Antibody (1A524)
Brand: abinScience
SKU: HY413035
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HY413035
Description	Anti-Human MPO Monoclonal Antibody (1A524) [1A524] (HY413035) is a mouse monoclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A524
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human MPO (Val165-Gly278).
Target	Myeloperoxidase, MPO, EC:1.11.2.2, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05164
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. 1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160 2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971
Note	For research use only.