Anti-MPO Polyclonal Antibody (HY413014)

Name: Anti-MPO Polyclonal Antibody
Brand: abinScience
SKU: HY413014
Price: 96 USD
Availability: InStock

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Aperçu

Numéro de catalogue

HY413014

Description

Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human MPO (Val165-Gly278).

Cible

Myeloperoxidase, MPO

Purification

Purified by antigen affinity column.

Numéro d'accès

P05164

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.

1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160

2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971

Note

For research use only.

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