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| カタログ番号 | HY413014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MPO (Val165-Gly278). | ||||||||
| ターゲット | Myeloperoxidase, MPO | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P05164 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. 1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160 2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-MPO polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate
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