

| Каталожный номер | HY413014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human MPO (Val165-Gly278). | ||||||||
| Цель | Myeloperoxidase, MPO | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P05164 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. 1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160 2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-MPO polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate




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